Alkyl nitrites can be very close to the true drug aphrodisiac. Approximately 250 million bottles a year are used in the United States. We will consider six aspects: chemistry, availability, mode of action, social use, toxicology, and legal trends. Alkyl nitrites - yellow flammable liquid with the aroma of different things to smell like fruit or old socks, a sports hall. They are unstable and decompose when exposed to light, if they are heated or under the influence of oxygen. There are several forms of the substance: Amila nitrite, used in cardiology for more than a century with angina butyl nitrite. From 1960 until 1969, nitrite Amila was a legitimate product, but was returned to the list of prescriptions issued, after hearing Farm Committee (FDA USA), apparently having regard to the economic policies of pharmaceuticals, as no sign of injury was not represented at the hearing. Consumption of nitrite Amila moved to the south-western border with Mexico, where no prescription was not needed for purchase. Butyl nitrite became available in major stores, bookstores, mail and a few wine shops. It is usually sold in capsules of 0.3 ml. They were stored in refrigerators and not exposed to sun. The main pharmacological action of nitrite is the relaxation of smooth muscles. His heartfelt como action - not in the direct effect, and in the relaxation system of arterioles, leads to a sharp drop in blood pressure, tachycardia, and reflected in the reduction of left ventricular training. Its action is most effective within 30 seconds, and returned to normal pressure is less than two minutes. A person feels a sense of warmth, dizziness. Psychological reaction varies with the initial installation or expectation, personal chemistry, ranging from happiness to soft outer nausea and headache. Mental actions arise from the effects on brain physiology. A recent review of research done on nitrite Amila since 1914, revealed the main effect of the brain - the expansion of the retinal and related to the pia mater arteries and capillaries, increasing brain levels and increased cerebral blood flow. There was a brief increase in cerebrospinal fluid pressure. Investigation of five volunteers showed no pathological changes. The usual response was a reaction to bring in readiness, with the change from alpha to beta waves. There were small changes in amplitude, which returned to normal within 15 minutes. Mathews (1981) studied changes in cerebral blood flow in response to butyl nitrite, using radioactive xenon. In short, volatile nitrites are turning to systematic blood pressure and increase cerebral blood flow. Social use of nitrites include dance and sexuality. In explicitly sexual plants, the use of poppers can be divided into two aspects: the psychological and sexual. When psychological installation Poppers gives the consumer experience more tactile and superficial feelings. Nitrite is reported to have a lot of women, are useful for covering the main sexual dysfunction - distraction. Poppers removes anxiety and peripheral thoughts about unfinished matters, child protection, identity or daily internal stimuli, which block the full sensation in order to achieve satisfaction during intercourse. Of course, no drug can not be used in place of trust, proximity, or replace their relationship, but in some moments Poppers can contribute to the process. The feeling of lack of sense of time, mixed with euphoria in the immediate moment is described by many consumers. The sexual act itself becomes easier, especially anal sex. It comes from a combination of muscle relaxation and decreased perception of pain. When inhaled poppers before orgasm, the user may experience a sense of excitement and more frequent orgasms. In this regard, he sees it as more intense and long. It is worth noting the most favorable ratio of harm and pleasure than for the majority of psychotropic chemicals. Approximately 250 million bottles per year used in the U.S. and there were no known deaths from inhalation. The most common toxic effects - headache, reported by 43% of consumers, at least in one case. However, most consumers are not experiencing headaches. The review 255 experiments (Lori 1979c), 10% experienced nasal irritation at least once, and five percent experienced nausea or temporary loss of erection. Using registration data, Swenson (1978) studied 20 men who used poppers in the average four times a day for seven years. The results were compared with no user controls. There was no significant difference, even if that utilizes nitrite group smoked a lot more tobacco and marijuana than the control group. It is noted that the abuse of drugs, in 1 350 000 cases, only 67 were associated with nitrite. There were no deaths. Review of 605 specialists in the department of emergency surgery (Lori 1979a), 592 had never seen a patient with poisoning after inhaling nitrites. Thirteen respondents reported that patients with transient headache or methemoglobinemia. To summarize toxicity, both forms of nitrite, seem relatively harmless when inhaled and definitely toxic when ingested or injected intravenously. Legal status of nitrite Amila clear: FDA approved this drug we write out a prescription. Legal status of the material varies in each state. Several states have banned its sale, usually on the basis of risk to health. In five years, California, Wisconsin, Connecticut, Texas and Pennsylvania took steps to ban the sale of butyl nitrite within their borders, but after the hearing, withdrew claims on account of lack of evidence of medical harm. Consumer Product Safety Commission has issued regulations on the labeling of several brands, for more explicit notation of warnings associated with the use.